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What is Potassium Iodide? Potassium iodide is a stable form of iodine that is used to protect the thyroid gland from radioactive iodine. When taken prior to or shortly after exposure, potassium iodide saturates the thyroid gland with non-radioactive iodine, reducing the absorption of radioactive iodine. This can significantly reduce the risk of developing thyroid cancer or other radiation-induced